Obesity Paradox and Stroke

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Obesity Paradox and Stroke

See related articles, pages 3397 and 3646. Obesity has a well-known association with initial incidence of cardiovascular disease, stroke, cancer, and early death. However, a growing number of studies have found that overweight and frankly obese patients who survive the first event tend to have improved subsequent cardiovascular (CVD)1,2 and cerebrovascular disease burden,3,4 morbidity, and mort...

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Body mass index and death by stroke: no obesity paradox.

IMPORTANCE Reports of an obesity paradox have led to uncertainty about secondary prevention in obese patients with stroke. The paradox is disputed and has been claimed to be an artifact due to selection bias. OBJECTIVE To determine whether the obesity paradox in stroke is real or an artificial finding due to selection bias. DESIGN, SETTING, AND PARTICIPANTS We studied survival after stroke ...

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obesity, heart failure, and obesity paradox

the incidence and prevalence of obesity are fast increasing worldwide. various indices have been used to measure and assess obesity. the body mass index (bmi) is the most common and practical of these indices. overweight and obesity exert considerable adverse effects on the cardiovascular system. these effects are mediated through various neurohormonal and cytokine pathways, most of which are i...

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Obesity paradox in stroke – Myth or reality? A systematic review

BACKGROUND AND PURPOSE Both stroke and obesity show an increasing incidence worldwide. While obesity is an established risk factor for stroke, its influence on outcome in ischemic stroke is less clear. Many studies suggest a better prognosis in obese patients after stroke ("obesity paradox"). This review aims at assessing the clinical outcomes of obese patients after stroke by performing a syst...

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Body weight after stroke: lessons from the obesity paradox.

BACKGROUND AND PURPOSE Outcome after acute stroke is determined to a large extent by poststroke complications. Nutritional status and metabolic balance may substantially contribute to outcome after stroke. Key mechanisms of stroke pathophysiology can induce systemic catabolic imbalance with impaired metabolic efficiency and degradation of body tissues. SUMMARY Tissue wasting, sarcopenia, and ...

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ژورنال

عنوان ژورنال: Stroke

سال: 2011

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.111.632471